SURGERY

The oldest prong of the lethal trident, cynically known as modern cancer therapy, is surgery. The notion being that the removal of a tumour cures the patient; ignoring the fact that cancer is a whole body, systemic disease which eventually manifests a tumour.

Surgery is a massive shock to the system, which uses carcinogenic anaesthesia and increases the risk of cancer in the scar tissue. It has a place only where the threat to life processes is immediate, as in digestive obstruction, artery pinch, etc.

Like all revolutionary ideas, this challenges conventional belief (dogma) that one can expect a knee jerk rejection from those who have an intellectual or financial investment in the status quo, to either ignore or react with irrational anger to our message. Our observations have enraged many “conventional” medicine zealots who then engage in a kind of ideological warfare against us or anyone who draws attention to this counter-intuitive observation. We prefer to simply stick to the science of the issue.

As Doctors, we are taught by the scientific method that there are experiments and there are theories. Theories are proposed to explain data and experiments are performed to test theories. When there is satisfactory agreement between theory and experiment we accept that the theory is likely valid and we can move on to study other things. But what happens when there is disagreement between theory and experiment? It does not matter how long the theory

has been around or who has endorsed it. If theory and experiment disagree, we are obligated by the scientific method to reexamine the theory and the facts surrounding it.

Those who ignore the facts are left to make uninformed decisions based on personal biases, and not science.

Peering into someone’s body is such an intimate act that many doctors detach themselves emotionally to handle the strain. Surgery, however, has become so commonplace that body parts are being removed and/or replaced at an unprecedented rate without mention of alternatives. Along with the rush to operate come the mistakes. Cutting off the wrong limb, operating on the wrong organ, and surgical tools left inside the body are mounting effects of a system out of control.

We suggest that cancer surgery bears significant risk of recurrence, a lack of effectiveness, kick-starts growth of dormant micrometastases and causes significant immune system dysfunction.

This has actually been known for over 100 years!

The Journal of Experimental Medicine, 1914; Vol. 20: pages: 404–412.
On the cause of the localization of secondary tumors at points of injury. By: Jones FS, Rous P.
“The localization of secondary tumors at points of injury has been so often remarked upon that it is unnecessary to cite specific instances…connective tissue, reacting to an injury, is in a condition to elaborate the stroma for a tumor more rapidly and abundantly than normal tissue.”

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[stroma– the supportive tissue of an epithelial organ, tumor, gonad, etc., consisting of connective tissues and blood vessels.]

After physical trauma such as surgery, the normal “wound healing” response creates a macrophage-mediated inflammatory milieu of cytokines, chemokines, and growth factors that promote tumor progression by facilitating tissue invasion, angiogenesis, and evasion of antitumor immunity [1–4].

1. Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet 2001;357:539–545. [CrossRef] [Medline]
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2. Chiang AC, Massague J. Molecular basis of metastasis. N Engl J Med 2008;359:2814–2823. [CrossRef] [Medline]

3. Nelson D, Ganss R. Tumor growth or regression: powered by inflammation. J Leukoc Biol 2006;80:685–690. [CrossRef] [Medline]

4. Nathan C. Points of control in inflammation. Nature 2002;420:846–852. [CrossRef] [Medline]

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Journal of the International Academy of Preventive Medicine, 6 (1) 23 – 39, 1979.
IS THE CURRENT TREATMENT OF CANCER SELF-LIMITING IN THE EXTENT OF ITS SUCCESS? By: Dr. Ernst H. Krokowski, M.D., Ph.D., Professor of Medicine (Radiology) and Chief of the Central Institute of Radiology of Kassel Hospital in Germany.

His research provided convincing proof that cancer surgery triggers metastasis.

Here are some key observations from his landmark article:

Inflated success rates [of cancer surgery] are the result of either selective composition of the groups of patients studied or of correspondingly adapted, i.e., corrected, statistics.

Cures related to the same stage and tumour size have not improved in the last 20 to 25 years [more recent findings state that the cure rate has not significantly increased since the 1970’s, which means that overall there was no significant improvement since the 1950’s].

Untreated postmenopausal women with breast cancer live longer than medically treated patients.

❹ Manipulation of a tumour, such as severe palpation and pressure [mammography], biopsy or surgery, results in a sudden increase of tumour cells released into the blood with a higher probability of metastasis.

The connection between surgery and formation of metastases was particularly impressive in single observed cases: in a patient with a sarcoma, formation of metastases occurred after surgery of the primary tumour and each time after four further surgeries of locally recurrent tumours.

It has long been taught in medicine that a melanoma should not be injured since lesions would cause an almost explosion-like growth of metastases.

❼ Not only disturbance of a tumour but also unrelated surgery at a different location can trigger metastasis.

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The relation between surgical trauma, wound healing, and tumour recurrence has been acknowledged since early observations of recurrent malignancies in operative wounds.[5-6] An association between surgical trauma and tumour development was furthermore supported by a number of experimental studies.[7-12] The amount of surgical trauma was found to correlate with the extensiveness of tumour recurrence.[11-13]

5. Schott A, Vogel I, Krueger U, Kalthoff H, Schreiber HW, Schmiegel W, Henne-Bruns D, Kremer B, Juhl H. Isolated tumor cells are frequently detectable in the peritoneal cavity of gastric and colorectal cancer patients and serve as a new prognostic marker. Ann Surg 1998;227:372-9.
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6. Meszoely IM, Lee JS, Watson JC, Meyers M, Wang H, Hoffman JP. Peritoneal cytology in patients with potentially resectable adenocarcinoma of the pancreas. Am Surg 2004;70:208-13; discussion 13-4.

7. Bouvy ND, Marquet RL, Hamming JF, Jeekel J, Bonjer HJ. Laparoscopic surgery in the rat. Beneficial effect on body weight and tumor take. Surg Endosc 1996;10:490-4. Bouvy ND
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8. Busch OR, Hop WC, Hoynck van Papendrecht MA, Marquet RL, Jeekel J. Blood transfusions and prognosis in colorectal cancer. N Engl J Med 1993;328:1372-6.
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9. van den Tol PM, van Rossen EE, van Eijck CH, Bonthuis F, Marquet RL, Jeekel H. Reduction of peritoneal trauma by using nonsurgical gauze leads to less implantation metastasis of spilled tumor cells. Ann Surg 1998;227:242-8.
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10. Raa ST, Oosterling SJ, van der Kaaij NP, van den Tol MP, Beelen RH, Meijer S, van Eijck CH, van der Sijp JR, van Egmond M, Jeekel J. Surgery promotes implantation of disseminated tumor cells, but does not increase growth of tumor cell clusters. J Surg Oncol 2005;92:124-9.
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11. Eggermont AM, Steller EP, Marquet RL, Jeekel J, Sugarbaker PH. Local regional promotion of tumor growth after abdominal surgery is dominant over immunotherapy with interleukin-2 and lymphokine activated killer cells. Cancer Detect Prev 1988;12:421-9.

12. van Rossen ME, Hofland LJ, van den Tol MP, van Koetsveld PM, Jeekel J, Marquet RL, van Eijck CH. Effect of inflammatory cytokines and growth factors on tumour cell adhesion to the peritoneum. J Pathol 2001;193:530-7.

13. M ten Kate, LJ Hofland, WMU van Grevenstein, PV van Koetsveld, J Jeekel, CHJ van Eijck. Influence of proinflammatory cytokines on the adhesion of human colon carcinoma cells to lung microvascular endothelium International Journal of Cancer
2004; 112: 943-950.
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Archives of Surgery, 2006;141:1132-1140. Cell Response to Surgery
By: Niamh Ni Choileain, MD; H. Paul Redmond, MCh, FRCSI
“Experimental and clinical studies have shown that surgical trauma profoundly affects the immune system, including both the innate and adaptive immune responses. Major surgical trauma promotes an immunologic dysfunction that predisposes the patient to significant morbidity…Importantly, the immunosuppressed state has also been associated with an increased rate of tumor progression and metastasis formation in patients with malignant disease.”
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American Cancer Society, Cancer Facts & Figures 2007
“Surgery, radiation therapy, and chemotherapy are treatment options that may extend survival and/or relieve symptoms in many patients, but seldom produce a cure.”
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The post-operative wound microenvironment provides advantageous conditions for tumour recurrence as tumour development is influenced by locally produced growth factors, inflammatory cytokines, and reactive oxygen species produced by inflammatory cells. [14,16] Additionally, surgery induced immune suppression resulting in impaired immunological defence against disseminated tumour cells can affect tumour development as well. [17, 18]

14. Hofer SO, Shrayer D, Reichner JS, et al. Wound-induced tumour progression: A probable role in recurrence after tumour resection. Arch Surg 1998;133:383.389.
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15. Busch OR, Hop WC, Hoynck van Papendrecht MA, et al. Blood transfusions and prognosis in colorectal cancer. N Engl J Med 1993;328:1372.1376.
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16. van Rossen ME, Sluiter W, Bonthuis F, et al. Scavenging of reactive oxygen species leads to diminished peritoneal tumour recurrence. Cancer Res 2000;60:5625.5629.
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17. Mels AK, Statius Muller MG, van Leeuwen PA, et al. Immunestimulating effects of low-dose perioperative recombinant granulocyte-macrophage colony-stimulating factor in patients operated on for primary colorectal carcinoma. Br J Surg 2001; 88: 539.544.

18. Sietses C, Beelen RH, Meijer S, et al. Immunological consequences of laparoscopic surgery, speculations on the cause and clinical implications. Langenbecks Arch Surg 1999;384: 250.258.

Additionally, solid tumour development required less tumour cells in wounded locations compared to non-wounded sites. [14] The reported increased risk of tumour recurrence that correlates with perioperative blood transfusions may be caused by the circumstances that necessitate them, such as extensive tissue trauma. [15]

Scientific American, November 1985, Volume 253, Number 5, Pages 51-59.
The Treatment of Diseases and The War Against Cancer, by Dr. John Cairns, M.D., of Harvard University: on page 56 the following is written: “It remains a depressing truth that fewer than 50 percent of cancer patients can be cured by surgery.”
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The Ecologist, Vol 28 No 2 – March / April 1998, pages 117-121
The Diversity and Effectiveness of Natural Cancer Cures, By: Walter Last
“After analysing cancer survival statistics for several decades, Dr. Hardin Jones, Professor at the University of California,concluded in 1975 that “patients are as well, or better off untreated.” Jones’ disturbing assessment has never been refuted. What’s more, three studies by other researchers have upheld his theory.”
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Inflammatory oncotaxis is the phenomenon in which mechanically injured tissues are predisposed to cancer metastases.

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It is proven that surgical trauma of normal tissue promotes implantation and/or growth of circulating cancer cells [19–23] and that extent of trauma influences the metastatic success rate of these circulating tumor cells [19]

19. Murthy, S.M.; Goldschmidt, R.A.; Rao, L.N.; Ammirati, M.; Buchmann, T.; Scanlon, E.F. The influence of surgical trauma on experimental metastasis. Cancer 1989, 64, 2035–2044.

20. Lee, J.Y.; Murphy, S.M.; Scanlon, E.F. Effect of trauma on implantation of metastatic tumour in bone in mice. J. Surg. Oncol. 1994, 56, 178–184.

21. Bogden, A.E.; Moreau, J.P.; Eden, P.A. Proliferative response of human and animal tumors to surgical wounding of normal tissues: onset, duration and inhibition. Br. J. Cancer 1997, 75, 1021–1027.
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22. Abramovitch, R.; Marikovsky, M.; Meir, G.; Neeman, M. Stimulation of tumour angiogenesis by proximal wounds: spatial and temporal analysis by MRI. Br. J. Cancer 1998, 77, 440–447.
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23. Abramovitch R.; Marikovsky M.; Meir G.; Neeman M: Stimulation of tumour growth by wound-derived growth factors. Br. J. Cancer 1999, 79, 1392–1398.
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2013 San Antonio Breast Cancer Symposium, presentation by Dr. Rajendra Badwe, M.D., “Patients With Metastatic Breast Cancer May Not Benefit From Surgery and Radiation After Chemotherapy.” [LRT refers to surgery and radiation treatments]
“We found that there was no difference in overall survival between those who received LRT and those who did not receive LRT,” explained Badwe. “Indeed, there was a 7 percent excess death rate in those who received LRT… surgical removal of the primary tumor bestows a growth advantage on metastases… We were unable to identify any subgroups that are likely to benefit from LRT.”
The study began with 350 women, 62% [218] were dead within 17 months.
Title: Surgical removal of primary tumor and axillary lymph nodes in women with metastatic breast cancer at first presentation: A randomized controlled trial.
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No Survival Benefit Found in LRT for Women Presenting With Metastatic Breast Cancer
LA Times“Some breast cancer patients don’t benefit from surgery or radiation”

The New England Journal of Medicine, 1995; 333: 1444-1456
Effects of Radiotherapy and Surgery in Early Breast Cancer — An Overview of the Randomized Trials, By The Early Breast Cancer Trialists’ Collaborative Group
The authors reviewed the results of all 36 randomized trials involving 28,405 women with early breast cancer. The 6% decrease in deaths from breast cancer were accompanied by a 24% increase in deaths due to other treatment-related causes, which demonstrates the damage caused by surgery. The study concluded that more radical local treatment, surgery or adjuvant radiotherapy does not have any influence on the appearance of distant disease or overall survival.
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The Journal of Clinical Investigation, May 1, 2007; 117(5): 1305–1313.
Published online Apr 5, 2007. doi: 10.1172/JCI30740
Inhibition of TGF-β with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression
Swati Biswas,1 Marta Guix,2 Cammie Rinehart,2 Teresa C. Dugger,2 Anna Chytil,1 Harold L. Moses,1,3,4 Michael L. Freeman,5 and Carlos L. Arteaga
“The repopulation and progression of tumors after anti-cancer therapy is a well-recognized phenomenon,” said the researchers. “It has been shown to occur following radiotherapy, chemotherapy, and surgery.”
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Treatment may fuel cancer’s spread, study finds.
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There is significant data showing surgery related spreading, especially in melanoma [24] and osteosarcoma [25].

24. Tseng,W.W.; Doyle, J.A.; Maguiness, S.; Horvai, A.E.; Kashani-Sabet, M.; Leong, S.P.L. Giant cutaneous melanomas: Evidence for primary tumour induced dormancy in metastatic sites? BMJ Case Rep. 2009, doi:10.1136/bcr.07.2009.2073.
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25. Kaya, M.; Wada, T.; Nagoya, S.; Yamashita, T. Prevention of postoperative progression of pulmonary metastases in osteosarcoma by antiangiogenic therapy using endostatin. J. Orthop. Sci. 2007, 12, 562–567.
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We got it all! [are you sure about that?]

Surgeons routinely tell cancer patients, “I got it all,” but studies show that cancer cells are left behind allowing the opportunity for malignant growths to recur.

Clinical Cancer Research, 2004 Dec 15;10(24):8152-62.
Circulating tumor cells in patients with breast cancer dormancy.
By: Meng et al.
Thirteen dormancy candidates, from 7 to 22 years after mastectomy and without evidence of clinical disease, had CTCs, usually on more than one occasion. The CTCs in patients whose primary breast cancer was just removed had a lifespan from 1 to 2.4 hours. The CTCs that are dying must be replenished every few hours by replicating tumor cells somewhere in the tissues. “Hence, there appears to be a balance between tumor replication and cell death for as long as 22 years…”
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Journal of the American Medical Association, 1992; 267(16):2191-2196 By: Johansson et al. High 10-Year Survival Rate in Patients With Early, Untreated Prostatic Cancer
This study in the Journal of the American Medical Association of 223 patients concluded that no treatment at all for prostate cancer actually was better than any standard chemotherapy, radiation or surgical procedure.
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Journal of the National Cancer Institute, 1997, Vol. 89, No. 14: 1044-1049.
Association of Tumor Angiogenesis With Bone Marrow Micrometastases in Breast Cancer Patients, By Fox et al.
“Despite apparent curative surgery, a large proportion of lymph node-negative breast cancer patients will die of metastatic disease that is undetected by conventional methods at presentation.”
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The New England Journal of Medicine, 1995; 333: 1496-1498
Surgery for Early Breast Cancer — Can Less Be More?
By: Dr. John C. Bailar, III, M.D., Ph.D., University of Chicago,
“The evidence is now persuasive that reducing the scope of surgical intervention for early breast cancer…has little or no effect on survival, at least in the short and midterm.”
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The New England Journal of Medicine, 1995; 333: 1456-1461
Reanalysis and Results after 12 Years of Follow-up in a Randomized Clinical Trial Comparing Total Mastectomy with Lumpectomy with or without Irradiation in the Treatment of Breast Cancer, By: Fisher et al.
“no significant differences were found in overall survival, disease-free survival, or survival free of disease at distant sites between the patients who underwent total mastectomy and those treated by lumpectomy alone or by lumpectomy plus breast irradiation.”
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The New England Journal of Medicine, 2002; 347:781-9.
A Randomized Trial Comparing Radical Prostatectomy with Watchful Waiting in Early Prostate Cancer. By: L Holmberg et al.
“…there was no significant difference between surgery and watchful waiting in terms of overall survival.”
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Different study 10 years later with the same result.

The New England Journal of Medicine, 2012; 367:203-213
Radical Prostatectomy versus Observation for Localized Prostate Cancer
By: Wilt et al. “…radical prostatectomy did not significantly reduce all-cause or prostate-cancer mortality, as compared with observation…”
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The Independent– Study raises doubts over treatment for prostate cancer
The Telegraph– Prostate cancer surgery ‘has no significant survival benefit’, study suggests
Daily Mail– Prostate cancer surgery ‘has little or no benefit’ in extending life of patients
Bloomberg– Prostate Cancer Surgery Fails to Cut Death Rate in Study
Cancer.org– Study: Surgery No Better Than Observation for Localized Prostate Cancer

Even older kidney tumor patients are MORE likely to die after surgery than if doctors waited to operate: study

New York Daily News– surgery roughly doubled patients’ risk of developing heart problems or dying of other causes
Telegram.com– a stunning example of when treatment might be worse than the disease
Oncology– Surveillance Safe for Small Kidney Tumors in Older Patients
NBC News- a stunning example of when treatment might be worse than the disease
USA Today– Study questions kidney cancer treatment in elderly
U.S. News & World Report– Study questions kidney cancer treatment in elderly
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Some of the best evidence regarding the lack of effectiveness for surgery comes from Medical Textbooks such as;

Medical Textbook- Essential Practice of Surgery: Basic Science and Clinical Evidence
2003 Springer-Verlag New York, Inc., 761 pages
By: Jeffrey A. Norton et al.
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Colorectal Cancer
“Debulking operations play only a minor role except for palliation of symptoms such as bleeding, bowel obstruction, and severe pain.” page 305

Thyroid Cancer
“There has been long-standing controversy concerning the appropriate extent of surgical resection for well-differentiated thyroid cancer.” page 383

Mesothelioma
“Currently, mesothelioma continues to defy any single treatment modality including surgery, chemotherapy, and radiation therapy.” page 536

Medical Hypotheses, (2014) 82, 412–420. The efficacy of surgical treatment of cancer – 20 years later, By: Donald J. Benjamin, Convenor/Research Officer, Cancer Information & Support Society, St Leonards, NSW, Australia
“Results: None of the seven indirect methods used showed that surgery clearly affects the course of the disease for any type of cancer. The lack of benefits from cancer screening now includes not only from breast cancer but also from bowel, lung, prostate and ovarian cancer screening. This confirms that cancer surgery is based on an invalid paradigm of what cancer is. Survival figures following treatments based on an alternative paradigm that assumes cancer is a systemic disease were found to be superior to those following surgery, reinforcing the conclusion that cancer is a systemic disease and that cancer surgery is unlikely to be of benefit in most cases.

Conclusion: No benefits can be expected to be achieved from using cancer surgery except in a few immediately life-threatening situations.

Surgery appears to be based on an invalid paradigm of what cancer is. Cancer appears to be a systemic disease and therefore standard treatments need to be reassessed in this light.”
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Women with unilateral breast cancer who elect to have both breasts removed derive no survival benefit from the extra surgery, according to a large study of 189,734 patients.

“There was no difference whatsoever, and we analyzed the data several ways using different statistical methods, so we feel the finding of no difference is quite robust,” said researcher Scarlett Lin Gomez, Ph.D., from Stanford University School of Medicine in Stanford, California. The sudy appears below.

Journal of The American Medical Association, September 3, 2014, Vol 312, No. 9
By: Kurian et al. Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011
Bilateral Mastectomy Yields No Survival Benefit
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Medical Hypothesis, 1993, Volume 40, Issue 2, pages 129-138
The efficacy of surgical treatment of cancer
By: D.J. Benjamin
“This paper is the result of a study to provide a scientific basis for the claim that surgery is effective in extending the life of cancer patients. The study failed to locate any scientifically valid evidence for the claim.”
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“A Report on Cancer”, speech delivered to the American Cancer Society’s 11th Annual Science Writers’ Conference by Dr. Hardin B. Jones, Ph.D., Professor of Medical Physics and Physiology, University of California, Berkeley.
“In regard to surgery, no relationship between intensity of surgical treatment and duration of survival has been found in verified malignancies….no studies have established the much talked about relationship between early detection and favorable survival after treatment….the specific death rates for common malignancies have remained essentially the same for persons of the same age over this entire century….[Regarding Cancer] such as those of the breast or the cervix, no relationship between dose and cure has been demonstrated, even though widely varying levels of treatment have been investigated.”
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Journal of the American Medical Association, 241(5):489-494,
On the Diagnosis and Treatment of Breast Cancer
“Those who refused medical procedures had a lower mortality rate than those who submitted” concluded Dr. Maurice Fox, Ph.D., Biologist from the Massachusetts Institute of Technology, based on a study completed at the Harvard School of Public Health.
Based on studies, Dr. Fox discovered many things, including:

  1. Complete mastectomy was no better than simple lump removal.
  2. The diagnosis of breast cancer was twice as frequent in 1975 than in 1935, and the death rate was also double, meaning no progress had been made in the attempt to cure cancer.
  3. A lower mortality rate was found in patients who refused medical procedures than those who submitted to conventional treatments.
  4. Early detection amounted to quicker treatment and earlier death.

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The New England Journal of Medicine, 1995; 333: 1444-1456
Effects of Radiotherapy and Surgery in Early Breast Cancer — An Overview of the Randomized Trials, By The Early Breast Cancer Trialists’ Collaborative Group
The authors reviewed the results of all 36 randomized trials involving 28,405 women with early breast cancer. The 6% decrease in deaths from breast cancer were accompanied by a 24% increase in deaths due to other treatment-related causes, which demonstrates the damage caused by the radiotherapy. The study concluded that more radical local treatment, surgery or adjuvant radiotherapy does not have any influence on the appearance of distant disease or overall survival.
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Cancers, 2010, 2, 305-337
Surgery Triggers Outgrowth of Latent Distant Disease in Breast Cancer: An Inconvenient Truth? By: Retsky et al.
This review cites a steady stream of studies showing that, it is better for patients to leave tumours alone.
That ideology runs contrary to the interest of the cancer industry for which invasive treatment is the financial life-blood.
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Here are some of the significant highlights from this landmark article:

❶ Getting women screened with mammography is a major goal of numerous organizations so the information (about possible harm) is rarely disclosed in public since it is thought that if women were told this they might not opt for mammography.

❷ During most of the 20th century radical mastectomy was the accepted therapy. Unfortunately, only 23% of patients survived 10 years. The natural response to this failure was even more radical surgery.

❸ The next step by medical oncologists was similar to that by surgeons: if a little doesn‘t work then try a lot! Needless to say the high dose chemotherapy with bone marrow rescue was a failure and the least said about this sorry episode in the history of breast cancer the better.

❹ Pathological and autopsy studies have suggested that most of the occult tumours in breast (and prostate cancers) never reach clinical significance.

❺ Cancer cells and micro-metastases remain in a state of dormancy until some signal, perhaps the act of surgery stimulates them into fast growth. The act of wounding the patient creates a favorable environment for the sudden transfer of a micro-metastasis from a latent to an active phase.

❻ A large primary tumour inhibits the development and growth of any distant metastases. Removal of the primary results in the establishment and rapid growth of large numbers of latent metastases, the majority of which would have remained dormant or would have disappeared if the primary tumour had not been removed. The growth-stimulating postoperative effects on pre-existing latent metastases are due to removal of the primary tumour.

Numerous studies have been carried out to measure the importance of radical surgery. All of these studies showed there was no difference in survival between women who underwent different degrees of surgery ranging from radical mastectomy to lumpectomy.

Fisher B et al. Five year results of a randomised clinical trial comparing Total Mastectomy and Segmental Mastectomy with or without radiation in the treatment of breast cancer. N Engl J Med 1985; 312 (11): 665.
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Fisher B et al. Ten year results of a randomised clinical trial comparing radical mastectomy and total mastectomy with or without radiation. N Engl J Med 1985; 312 (11): 674.
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Fisher B et al. Eight year results of a randomised clinical trial comparing total mastectomy and lumpectomy with or without irradiation in the treatment of breast cancer. N Engl J Med 1989; 320: 822 828.
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Fisher B et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002 Oct 17; 347 (16): 1233-41.
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Fisher B et al. Twenty-Five-Year Follow-up of a Randomized Trial Comparing Radical Mastectomy, Total Mastectomy, and Total Mastectomy Followed by Irradiation.. N Engl J Med. 2002 Aug 22; 347 (8): 567-575.
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Veronesi U et al. Comparing Radical Mastectomy with Quadrantectomy, Axillary Dissection and Radiotherapy in patients with small cancers of the breast. N Engl J Med. 1981; 305 (1): 6.
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Sarrazin L et al. Conservative Treatment versus Mastectomy in Breast Tumors with Macroscopic Diameter of 20 Millimeters or Less. Cancer 1984; 53 (5): 1209-1213.
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These results show the relevance of the comment made in 1963 by eminent cancer researcher Michael Shimkin that “when many forms of treatment appear to yield the same results or lack thereof suspicion should arise that none is really effective and a no-treatment group in subsequent comparisons may be acceptable”.
Shimkin MB. The Numerical Method in Therapeutic Medicine, Public Health Reports 1964; 79 (1): 1-12.
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Despite what Shimkin said, no randomised trials have been held to compare surgery with no treatment. Such a trial would be considered unethical today because it would involve withholding a “proven” treatment to demonstrate its efficacy. Such is the tortured logic of the medical profession. So the profession has locked itself in to an unproven method.

The Journal of Clinical Investigation, May 1, 2007; 117(5): 1305–1313.
Published online Apr 5, 2007. doi: 10.1172/JCI30740
Inhibition of TGF-β with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression|
Swati Biswas,1 Marta Guix,2 Cammie Rinehart,2 Teresa C. Dugger,2 Anna Chytil,1 Harold L. Moses,1,3,4 Michael L. Freeman,5 and Carlos L. Arteaga
“The repopulation and progression of tumors after anti-cancer therapy is a well-recognized phenomenon,” said the researchers. “It has been shown to occur following radiotherapy, chemotherapy, and surgery.”
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Treatment may fuel cancer’s spread, study finds.
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Cancer: Principles and Practice of Oncology 6th edition (July 2001): by Vincent T. Devita, Samuel Hellman & Steven A. Rosenberg. By Lippincott Williams & Wilkins Publishers.
Dr. Vincent T. Devita, M.D.
Former Director of The NCI (National Cancer Institute) and the National Cancer Program
Former Director of Yale Cancer Center
Current Professor at Yale Medical School
Editor-in-chief of The Cancer Journal
“a risk of peritoneal dissemination of tumor cells resulting from surgical manipulation and intraoperative large-needle biopsy is supported by data from Staley et al.” p.821

“The risk of colorectal cancer spread caused by surgical manipulation is well recognized.” p.890

“Implantation may occur when cancer cells are shed intraluminally, from the serosal surface, and by surgical manipulation.” p.890
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Surgical Oncology, August 1994, Volume 3, Issue 4, Pages 211–219
Natural immunity in breast cancer patients during neoadjuvant chemotherapy and after surgery, By: Beitsch et al. “We conclude that the initial treatment of breast cancer patients, whether it involves surgery alone or with neoadjuvant chemotherapy, profoundly impairs their natural immune system and could increase the risk of metastasis.”
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Breast Cancer Research, 2004, 6:R372-R374
Hypothesis: Induced angiogenesis after surgery in premenopausal node-positive breast cancer patients is a major underlying reason why adjuvant chemotherapy works particularly well for those patients. By Retsky et al.
“After the primary tumor is resected, the angiogenic switch is thrown and the lung metastases start to grow rapidly…it may be said that results of adjuvant chemotherapy have plateaued.”
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In a shocking paper published in 2005 in the International Journal of Surgery, researchers theorized that removing cancerous tumors from the breast causes the body to release certain compounds that enable cancer cells that had been in hibernation to wake up and start growing.

International Journal of Surgery, (2005) 3 , 179 e 187
Does surgery induce angiogenesis in breast cancer? Indirect evidence from relapse pattern and mammography paradox. By Retsky et al.
“…surgery to remove a primary breast tumor can induce angiogenesis of dormant distant disease…Well-intentioned sweeping this problem under the rug has not been helpful.”
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The Wall Street Journal, Sept. 13, 2005, page D1, “Some Researchers Say Removing A Tumor Can Trigger a Process That Leads to New Growth…over half of all relapses in breast cancer are accelerated by surgery.”
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AANA Journal, August 2009, Vol. 77, No. 4, Pages 287-292
Effects of Anesthetics and Analgesics on Natural Killer Cell Activity
By: Welden et al.
“Surgical excision of cancerous tumors and the human stress response can lead to metastasis of tumor cells…surgery and anesthesia have been demonstrated to suppress NK cell activity, thereby placing patients with cancer at risk of metastasis.”
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Surgical Oncology Clinics of North America, 12 (2003) 127–134.
Are there indications for chemotherapy in hepatocellular carcinoma?
By: Dr. Philip J. Johnson, MD, FRCP, University of Birmingham, United Kingdom.
“Even among those who undergo surgical resection, there is a recurrence rate of up to 83% at 5 years.”
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Medical Hypothesis, 1996, Volume 47, Issue 5, pages 389-397
The efficacy of surgical treatment of breast cancer
By: D.J. Benjamin
“Claims that mammographic screening reduces breast cancer mortality are therefore unproven. The conclusion from the previous analysis, that surgery has not been shown to reduce mortality for any form of cancer, is therefore still valid.”
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European Journal of Surgical Oncology, 1998 Dec;24(6):477-86.
Screening for colorectal cancer: present, past and future. By: Anwar, Hall and Elder.
“Despite a better understanding of the genetics, and advancement in surgical and anaesthetic techniques, there has been little reduction in mortality and morbidity from this disease over the past 25 years.”
http://www.ejso.com/article/S0748-7983%2898%2993176-6/abstract
http://www.ncbi.nlm.nih.gov/pubmed/9870720

The Lancet 2:316-19, 1985
False Premises and False Promises of Breast Cancer Screening, By Skrabanek
“The evidence that breast cancer is incurable is overwhelming. The philosophy of breast cancer screening is based on wishful thinking that early cancer is curable cancer, though no-one knows what is “early”. Unable to admit ignorance and defeat, cancer propagandists have now turned to blaming the victims: they consume too much fat, they do not practise breast self-examination, they succumb to “irrational” fears and delay reporting the early symptoms. It would appear that no woman needs to die of breast cancer if she reads and heeds the leaflets of the cancer societies and has her breasts examined regularly. Adherence to these myths and avoidance of reality undermines the credibility of the medical profession with the public.”
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The Breast, February 2015, Volume 24, Issue 1, Pages 32–37
Is there a role for locoregional surgery in stage IV breast cancer? By: E.M. Quinn et al.
“Current guidelines do not recommend locoregional surgery for Stage IV breast cancer…”
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Surgery severely damages your immune system, and has been found to reduce the activity of natural killer cells by 96%! [26] So if there are tumours growing elsewhere in the body, then surgery could make things far worse by allowing more rapid growth of other tumours. Curing cancer cannot be done by destroying the body’s immune system! These defenses also won’t quickly return to normal.[27]

26. Surgical Oncology, August 1994, Volume 3, Issue 4, Pages 211–219
Natural immunity in breast cancer patients during neoadjuvant chemotherapy and after surgery
By: Beitsch et al. “We conclude that the initial treatment of breast cancer patients, whether it involves surgery alone or with neoadjuvant chemotherapy, profoundly impairs their natural immune system and could increase the risk of metastasis.”
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27. Nursing Research, 2009 ; 58(2): 105–114
Significant Impairment in Immune Recovery Following Cancer Treatment
By: Kang et al. “Significant delays in immune recovery and large variability persisted at 12 months, which was at least 6-10 months after the completion of any adjuvant therapy.”
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Dr. Michael Baum, M.D., a leading British breast cancer surgeon, found that breast cancer surgery tends to increase the risk of relapse or death within three years. He also linked surgery to accelerating the spread of cancer by stimulating the formation of metastases in other parts of the body. “Does surgery disseminate or accelerate cancer?”, in The Lancet, 347:260 (January 27, 1996)

Breast Cancer Research, 2004; 6(4): 160–161.
Does the act of surgery provoke activation of “latent” metastases in early breast cancer?
By: Professor Michael Baum, M.D.
“Perhaps now that we have a mechanism to explain this finding, the more open minded in the scientific community might begin to believe in it.”
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The Lancet Oncology, 2003; 4: 760–68 Excisional surgery for cancer cure: therapy at a cost
By: Coffey et al.
Several studies have shown increased metastatic growth after primary tumour removal.[28] These studies are substantiated by a large body of experimental data showing increased metastasis after surgery. [29, 30] Reports are accumulating that indicate that relatively minor surgical processes such as wound biopsy or gamma knife irradiation are associated with tumour progression. [31,32] The process of tumour removal alters the biological properties (ie, proliferation, apoptosis, and metastatic properties) of neoplastic cells. It has been suggested that multiple wounds from breast biopsy may have a similar effect. [33]
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28. O’Reilly MS, Shing Y, Fukai N, et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 1997; 88: 277–85.
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29. Pidgeon GP, Harmey J, Kay E, et al. The role of endotoxin/lipopolysaccharide in surgically induced tumour growth in a murine model of metastatic disease. Br J Cancer 1999; 81: 1311–17.
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30. Coffey JC, Doyle M, O`Mahony L, et al. Probiotics confer protection against perioperative metastatic tumour growth. Annals of Surgical Oncology 2001; 89: 643.
http://www.annsurgoncol.org/journals/articlelist.html?v=8&j=10434&i=4 Article is censored from website
http://archsurg.jamanetwork.com/article.aspx?articleid=398515 references the censored article

31. Shin M, Ueki K, Kurita H, Kirino T. Malignant transformation of a vestibular schwannoma after gamma knife radiosurgery. Lancet 2002; 202: 309–10.

32. Malignant Transformation of Acoustic Neuroma/Vestibular Schwannoma 10 Years after Gamma Knife Stereotactic Radiosurgery. SKULL BASE/VOLUME 20, NUMBER 5 2010
Demetriades, Saunders & Rose, et al. 381-387
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33. Retsky M, Demicheli R, Hrushesky W. Wounding from biopsy and breast-cancer progression. Lancet 2001; 357: 1048.
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Metastasis is commonly triggered by medical intervention

The Lancet, 362 : 527 – 533, Role of HER2 in wound-induced breast carcinoma proliferation.
By: Tagliabue, et al.
“…our data suggest that any surgical treatment undertaken in a patient with cancer, even those other than the removal of the primary tumour, could lead to promotion of tumour recurrence.”
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The Milbank Memorial Fund Quarterly. Health and Society;55(3):405-28
The questionable contribution of medical measures to the decline of mortality in the United States in the twentieth century. By: McKinlay and McKinlay
“In general, medical measures (both chemotherapeutic and prophylactic) appear to have contributed little to the overall decline in mortality in the United States since about 1900…”
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International Journal of Health Services. 1989, 19(23):181-208
A Review of the Evidence Concerning the Impact of Medical Measures on Recent Mortality and Morbidity in the United States, By: McKinlay, J.B. et al..
This epidemiological study confirmed the questionable value of conventional therapy by concluding that “medical interventions for cancer have had a negligible or no effect on survival”.

Surgery, April 2013, Volume 153, Issue 4, Pages 465–472
Surgical never events in the United States, By: Mehtsun et al
This study found that surgeons operated on the wrong part of the body 2,413 times between 1990 and 2010. They left foreign objects behind in the body (typically sponges) 4,857 times. In 27 cases, they operated on the wrong patient altogether.
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Shouldn’t the medical technology we use be rooted in a foundation of good and tested science? The answer is yes, but this just doesn’t happen most of the time.

The United States Congressional Office of Technology Assessment reviewed current medical practice in the United States to determine how much day to day practice was tested by the scientific method. Its report, Assessing the Efficacy and Safety of Medical Technologies, astonished those who believe in the myth of modern scentific medicine. It concluded that “only 10 to 20 percent of all procedures currently used in medical practice have been shown to be efficacious [effective] by controlled trial.” In other words, most of what is being done, has never been tested…
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British Medical Journal, 1991 Oct 5;303(6806):798-9
Where is the wisdom. ..? The poverty of medical evidence
By: Dr. Richard Smith, former editor of the British Medical Journal and chief executive of the BMJ publishing Group for 13 years.
“Only about 15% of medical interventions are supported by solid evidence…This is partly because only 1% of the articles in medical journals are scientifically sound, and partly because many treatments have never been assessed at all.”
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Journal of Evaluation in Clinical Practice, (2007), 13, 481–503
Medicine and evidence: knowledge and action in clinical practice, By: A. Miles et al.
“A fundamental assumption of EBM (Evidence Based Medicine)… is that doctors who practise it provide superior clinical care compared to those who do not…so far no convincing direct evidence exists that shows that this assumption is correct…It is noteworthy that the advocates of EBM (Evidence Based Medicine) have consistently avoided the organisation of, or involvement in, this most fundamental of scientific processes – the testing of an hypothesis…its advocates do not cite this one, single fundamental and serious deficiency – the complete lack of an evidentiary basis of EBM (Evidence Based Medicine).”
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Cancer patients who do NOTHING to treat their cancer can have far better success than risky surgeries. In the following recent study, as many as 22% of invasive breast cancers in Norwegian women disappeared spontaneously.

Archives of Internal Medicine, 2008; 168(21):2311-2316.The Natural History of Invasive Breast Cancers Detected by Screening Mammography, By: Per-Henrik Zahl, MD, PhD; Jan Mæhlen, MD, PhD; H. Gilbert Welch, MD, MPH.
In two study groups of 100,000 women, more than one in five invasive cancers detected in the study by mammography vanished without ever being treated!
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Dartmouth University story
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The New York Times,Study Suggests Some Cancers May Go Away”
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Dr. Barnett Kramer, M.D., M.P.H., director of the Office of Disease Prevention at the National Institutes of Health, is quoted in the article saying, “People who are familiar with the broad range of behaviors of a variety of cancers know spontaneous regression is possible, But what is shocking is that it can occur so frequently.”

That just goes to show the value of your immune system.

med-procedures-thenandnow-infog-02

chemo-radiation-and-surgery-are-largely-ineffectiveSurgery is not very effective

no-real-progress-against-cancerNo real progress against Cancer

oncology-mindsetOncology Mindset

breast-surgery-most-is-unnecessaryMost breast surgery is unnecessary

is-stage-4-cancer-curable-using-chemotherapy-radiation-or-surgeryIs Stage 4 Cancer curable using Surgery, Chemotherapy or Radiation?

patients-pressured-by-oncologistPatients pressured by oncologist

nci-director-and-overoptimism-about-cancerNCI Director and Overoptimism about Cancer

99-percent-of-oncologists-still-dont-understand-nutrition99 Percent of Oncologists Still Dont Understand Nutrition

big-pharma-financial-drivers-of-education-and-careBIG PHARMA Financial drivers of education and care

abc-news-the-prevalence-of-hospital-errorsABC news the prevalence of hospital errors

how-successful-are-clinical-trialsHow successful are clinical trials?

excited-about-a-clinical-trial-not-so-fastExcited about a clinical trial? Not so fast

how-effective-is-typical-oncologyHow effective is typical oncology

healing-cancer-from-inside-out-fullHealing Cancer from Inside Out Full

blind-faith-in-science-is-often-misplacedBlind faith in science is often misplaced

are-there-frauds-in-cancer-treatmentAre there frauds in Cancer treatment

why-chemo-radiation-and-surgery-cant-workWhy surgery, radiation and chemo cant work

the-chemo-radiation-surgery-industry-wont-go-awayThe surgery, chemo, radiation industry wont go away

surgery-radiation-and-chemo-cannot-work-against-the-stem-cellsSurgery radiation and chemo cannot work against the stem cells

surgery-is-largely-ineffectiveSurgery is largely ineffective

is-stage-4-cancer-curable-using-chemotherapy-radiation-or-surgeryDeath by Doctor with surgery, chemo and radiation

chemo-surgery-and-radiation-are-not-very-effectiveSurgery, chemo and radiation are not very effective

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