THE ORIGIN OF
CHEMOTHERAPY

Chemotherapy is a relatively recent development with its historical origins in observations of the toxic effects on humans exposed to chemical warfare agents, mainly mustard gas, during WWI and WWII, and to experimental studies of these agents used systemically in animals and humans preceding and during WWII.

Mustard gas is the common name for 1,1-thiobis(2-chloroethane), a vesicant chemical warfare agent synthesized by Frederick Guthrie in 1860 and first used near Ypres (Belgium) during WWI. Thus, its alternate name, Yperite.

frederick_guthrieBecause it could penetrate masks and other protective materials available during WWI, and given its widespread use by both sides of the conflict, its effects were particularly horrific and deadly. Out of 1,205,655 individuals exposed to Mustard gas during WWI, 91,198 died [1].

wwi-chemical-agentIt was at this time that mustard gas victims were first noted to develop low white blood cell counts and bone marrow aplasia. In a landmark study [2], a group of researchers at the University of Pennsylvania conducted autopsies on 75 soldiers who died of exposure to mustard gas during WWI, and reported decreased white blood cell counts and depletion of the bone marrow and lymphoid tissues. Shortly thereafter, military researchers from the US Chemical Warfare Service reported the same effects in rabbits injected intravenously with dichloroethylsulfide contaminated with mustard gas [3]. Fifteen years later the anti-cancer activity of mustard gas in experimental animal models was reported for the first time [4].

During WWII, the US’s Office of Scientific Research and Development (OSRD) funded Yale University to conduct, in secrecy, chemical welfare research [5]. These studies lead to the confirmation of the anti-tumor activity of mustard gas in murine lymphoma, and to the first human trials of nitrogen mustard reported at a Chicago meeting in early 1943 [6]. However, what brought the medical community’s attention to the Yale’s group studies and launched the era of cancer chemotherapy was a WWII incident when humans were accidentally exposed to mustard gas released during the bombardment of the Italian town of Bari by the German Luftwaffe, on December 2, 1943.


top-secret-bari-2nd-december-1943


Bari was a usually sleepy town of approximately 65,000 people located on the Adriatic shore of the Italian “boot”. Old Bari, perched on a promontory around its medieval fortified Castello Normanno Svevo and the Basilica San Nicolo, and new Bari, were transformed in late 1943 by the arrival of approximately 30 allied ships in its small harbor. Under British jurisdiction, Bari was the main supply center for British General Montgomery’s Army, and had just been designated headquarters of the American Fifteenth Air Force division.

bari-03-jpgOn the afternoon of December 2, 1943, 1st Lt. Werner Hahn piloted his Messerschmitt Me-210 reconnaissance plane over the port of Bari, in southeastern Italy. Cruising at 23,000 feet, his aircraft made a telltale contrail as he streaked across the sky, but Allied anti-aircraft crews took little notice. Still unmolested, the German pilot made a second pass over the city before turning north toward home. If Hahn’s report was promising, the Luftwaffe would launch a major airstrike against the port. Hahn reported to his superiors the suitability of Bari as a target for an air strike.

messerschmitt-me210As 1943 drew to a close, Bari’s medieval torpor and somnolent grace were shaken off by the influx of Allied shipping into its harbor. Tons of supplies were offloaded almost around the clock, transforming the once quiet town into a hive of activity. On December 2, at least 30 Allied ships were crowded into the harbor, packed so tightly they almost touched.

The port was under the jurisdiction of the British, in part because Bari was the main supply base for General Bernard Law Montgomery’s Eighth Army. But the city was also the newly designated headquarters of the American Fifteenth Air Force, which had been activated in November of that year. The Fifteenth’s primary mission was to bomb targets in the Balkans, Italy and especially Germany. Fifteenth Air Force commander Maj. Gen. James H. ‘Jimmy’ Doolittle had arrived in Bari on December 1.

The Americans had championed daylight precision bombing, but the Eighth Air Force in England was suffering terrible casualties in order to prove the theory valid. Luftwaffe strength was increasing, not decreasing, over Germany. The Fifteenth Air Force was intended to take some of the pressure off the beleaguered Eighth.

In addition to the usual war materiel, ships moored at Bari carried aviation fuel for Doolittle’s bombers and other much-needed supplies. Selection of Bari as the Fifteenth Air Force headquarters–about 75 miles from the Fifteenth’s primary airfields at Foggia–meant a large infusion of staff personnel. About 200 officers, 52 civilian technicians and several hundred enlisted men were being brought into the city.

Totally absorbed by the task of getting the Fifteenth Air Force off the ground, the Allies gave little thought to the possibility of a German air raid on Bari. The Luftwaffe in Italy was relatively weak and stretched so thin it could hardly mount a major effort. Or so Allied leaders believed.

German reconnaissance flights over Bari were seen as a nuisance. At first, British anti-aircraft batteries fired a half-hearted round or two, but eventually they ignored the German flights altogether. Why waste ammunition?

Responding to rumblings about lax security measures, British Air Vice Marshal Sir Arthur Coningham held a press conference on the afternoon of December 2 and assured reporters that the Luftwaffe was defeated in Italy. He was confident the Germans would never attack Bari. “I would regard it as a personal affront and insult,” the air marshal haughtily declared, “if the Luftwaffe would attempt any significant action in this area.” he would also “consider it a personal insult if the enemy should send so much as one plane over the city”.

sir-arthur-conningham

Not everyone was so sure that the German air force was a broken reed. British army Captain A.B. Jenks, who was responsible for the port’s defense, knew that preparations for an attack were woefully inadequate. But his voice, as well as those of one or two others, was drowned out by a chorus of complacent officers. When darkness came, Bari’s docks were brilliantly lit so unloading of cargo could continue. Little thought was given to the need for a blackout.

In the harbor, cargo ships and tankers waited their turn to be unloaded. Captain Otto Heitmann, skipper of the Liberty ship SS John Bascom, went ashore to see if the process could be speeded up. He was disappointed in his quest, but he might have been even more concerned had he known what was aboard SS John Harvey.

ss-john-herveyJohn Harvey, commanded by Captain Elwin F. Knowles, was a typical Liberty ship, scarcely different from the others moored in the harbor. Much of her cargo was also conventional: munitions, food and equipment. But the ship had a deadly secret cargo. Approximately 100 tons of mustard gas bombs were on board. The bombs were meant as a precaution, to be used only if the Germans resorted to chemical warfare.

In 1943 there was a possibility that the Germans just might use poison gas. By that point in the war, the strategic initiative had passed to the Allies, and Germany was on the defensive on all fronts. Adolf Hitler’s forces had sustained a major defeat at Stalingrad, and they had lost North Africa as well. The Allies were now on the Continent, slowly inching their way up the Italian peninsula.

Hitler, it was said, was not a great advocate of chemical warfare, perhaps because the Führer himself had been gassed during World War I. He was, however, ruthless and might be persuaded to use gas if he believed it would redress the strategic balance in his favor. Intelligence reports suggested that the Germans were stocking chemical weapons, including a new chemical agent called Tabun.

American President Franklin D. Roosevelt issued a policy statement condemning the use of gas by any civilized nation, but he pledged that the United States would reply in kind if the enemy dared to use such weapons first. John Harvey was selected to convey a shipment of poison gas to Italy to be held in reserve should such a situation occur.

When the mustard gas bombs were loaded aboard John Harvey, they looked deceptively conventional. Each bomb was 4 feet long, 8 inches in diameter and contained from 60 to 70 pounds of the chemical. Mustard is a blister gas that irritates the respiratory system and produces burns and raw ulcers on the skin. Victims exposed to the gas often suffer an agonizing death.

The poison gas shipment was shrouded in official secrecy. Even Knowles was not formally informed about the lethal cargo. Perceptive members of the crew, however, must have guessed the voyage was out of the ordinary. For one thing, 1st Lt. Howard D. Beckstrom of the 701st Chemical Maintenance Company was on board, along with a detachment of six men. All were expert in handling toxic materials and were obviously there for a purpose.

John Harvey crossed the Atlantic without incident, successfully running the gantlet of German submarines that still infested the ocean. After a stop at Oran, Algeria, the ship sailed to Augusta, Sicily, before proceeding to Bari. Lieutenant Thomas H. Richardson, the ship’s cargo security officer, was one of the few people on board who officially knew about the mustard gas. His manifest clearly listed 2,000 M47A1 mustard gas bombs in the hold.

m47Richardson naturally wanted to unload the deadly cargo as soon as possible, but when the ship reached Bari on November 26, his hopes were dashed. The harbor was crammed with shipping, and another convoy was due shortly. Dozens of vessels were stacked up along the piers and jetties, each waiting its turn to be unloaded. Since the lethal gas was not officially on board, John Harvey was not about to be given special priority.

For the next five nerve-racking days, John Harvey rode peacefully at anchor at Pier 29 while Captain Knowles tried vainly to get British port officials to speed things up. This was difficult, because he was gagged by the secrecy that surrounded the gas shipment. How could he get officials to act when he was not even supposed to know that he was carrying the mustard gas in the first place?

While Knowles fretted, German reconnaissance pilot Hahn had returned to base. His positive report about conditions at Bari set in motion a raid that had been discussed and planned some time before. The Bari attack was the product of a planning session between Luftwaffe Field Marshal Albert Kesselring and his subordinates. The Allied airfields at Foggia were discussed as possible targets, but Luftwaffe resources were stretched too thin to permit the effective bombing of such a large complex of targets.

It was Field Marshal Wolfram von Richthofen, commander of Luftflotte 2, who suggested Bari as an alternative. A cousin of famed World War I ace Manfred von Richthofen, the field marshal was an experienced officer who had served in Poland and the Soviet Union as well as in the Battle of Britain. His advice, Kesselring knew, was sound. Richthofen believed that if the port was crippled, the British Eighth Army’s advance might be slowed and the nascent Fifteenth Air Force’s bomber offensive delayed. Richthofen told Kesselring that the only planes available for such a task were his Junkers Ju-88 A-4 bombers. With luck, he might scrape together 150 such planes for the raid.

When the strike force was mustered, there were only 105 Ju-88s available for the mission. But the element of surprise, coupled with an attack at dusk, might shift the odds in the Germans’ favor. Most of the planes would come from Italy, but Richthofen purposely wanted to obfuscate matters by using a few Ju-88s from Yugoslavia. If the Allies thought the entire mission originated from there, they just might misdirect retaliatory strikes to the Balkans.

flightgermanju88sThe Ju-88 pilots were ordered to fly their twin-engine bombers east to the Adriatic, then swing south and west. British anti-aircraft would probably expect an attack–if any–to come from the north, not from the west. The Ju-88s were also supplied with Duppel, thin strips of tinfoil cut to various lengths. The tinfoil registered like aircraft on radar screens, producing scores of phantom targets.

The aim of the German pilots was to arrive over Bari around 7:30 p.m. Parachute flares would be released first to light the way for the attacking aircraft, and the Ju-88s would come in low, trying to get under Allied radar that was already confused by the Duppel.

The Germans arrived at Bari on schedule. First Lieutenant Gustav Teuber, leading the first wave, could hardly believe his eyes. The docks were brilliantly lit; cranes stood out in sharp relief as they unloaded cargo from the ships’ gaping holds, and the east jetty was packed with ships.

Scores of Ju-88s descended on Bari like gigantic birds of prey, their attack illuminated by the city’s lights and German flares. The first bombs hit the city proper, great geysers of smoke and flame marking each detonation, but soon it was the harbor’s turn. Some 30 vessels were riding at anchor that night, and each ship’s crew had to respond to the emergency as best they could. Surprise was total, and some ships had to function without a full complement, since many sailors were on shore leave.

The German flares gave sailors the first inkling of the impending attack. Aboard John Bascom, the second officer, William Rudolf, saw the flashes and alerted Captain Heitmann. John Bascom‘s gun crew sprang into action, joining the barrage that shore batteries were now hurling into the sky. Tracer bullets laced the air, but the anti-aircraft fire was largely ineffective.

There was no time to cut anchor cables and get underway; crews along the east jetty watched helplessly while a creeping barrage of German bombs came ever closer to their vulnerable vessels. Joseph Wheeler took a direct hit and exploded into flames; John Motley took a bomb in its No. 5 hold. John Bascom, anchored next to John Motley, was next in line for punishment.

highflight-disaster-at-bari4John Bascom shuddered under a rain of bombs that hit her from stem to stern. One of the explosions lifted Captain Heitmann off his feet and slammed him against the wheelhouse door. Momentarily stunned, his hands and face bloody, Heitmann saw the body of Nicholas Elgin sprawled nearby, blood pumping from a head wound, his clothes torn off by the force of the blast.

The ship’s bridge was partly destroyed, the decks were buckled and debris was everywhere. There was nothing left to do but abandon ship. Ignoring his own wounds, Heitmann ordered the crew into the single undamaged lifeboat. By now, the entire harbor was a hell on earth, where yellow-orange flames leaped into the air, producing dense columns of acrid smoke. Ships were in various stages of burning or sinking. When flames reached munitions-laden holds, some exploded. The surface of the water was covered by a viscous scum of oil and fuel, blinding and choking those unlucky enough to be in the water.

Meanwhile, the crew of John Harvey was engaged in a heroic battle to save their ship. The vessel still was intact and had sustained no direct bomb damage. Nevertheless, she had caught fire, and the situation was doubly dangerous with the mustard gas bombs aboard. Captain Knowles, Lieutenant Beckstrom and others on board refused to leave their posts, but their heroism was ultimately in vain.

Without warning, John Harvey blew up, disappearing in a huge, mushroom-shaped fireball that hurled pieces of the ship and her cargo hundreds of feet into the air. Everyone on board was killed instantly, and all over the harbor the force of the concussion knocked men off their feet. The blast sent out multihued fingers of smoke like a Fourth of July fireworks celebration and made the harbor as bright as day.

robert-rowan_archeoclub-gela-it_01The men aboard USS Pumper, a tanker carrying aviation fuel, were witnesses to John Harvey‘s last moments. Air initially rushed into the vortex of the blast, then the concussion radiated out to knock the tanker 35 degrees to port. Pieces of the chemical bombs were thrown hundreds of feet in all directions, and tons of mustard oil were vaporized.

Meanwhile, Heitmann and his surviving crew managed to reach the tip of the east jetty, around a lighthouse that was located at its north end. He had about 50 men. Many were badly wounded, and some were so badly burned that the slightest touch brought agony. At first the lighthouse area seemed a refuge, but it soon became apparent it was more of a deathtrap. A sea of flames cut Heitmann and his men off from following the jetty’s long spine into the city, where they might have been relatively safe.

While the sailors waited to be rescued, Ensign K.K. Vesole, commander of John Bascom‘s armed guard detachment, was having difficulty breathing. Many of the other men were gasping, but it was Vesole who noted something strange about the smoke. ‘I smell garlic,’ he said, without realizing the implications of his remark. A garlic odor was a telltale sign of mustard gas. The gas had become liberally intermixed with the oil that floated in the harbor and lurked in the smoke that permeated the area.

Mustard gas-laced oil now coated the bodies of Allied seamen as they struggled in the water, and many swallowed the noxious mixture. Even those not in the water inhaled liberal doses of gas, as did hundreds, perhaps thousands, of Italian civilians. A launch dispatched from Pumper rescued Captain Heitmann and the other John Bascom survivors from the east jetty, but their troubles were just beginning.

The German raid began at 7:30 p.m. and ended 20 minutes later. German losses were very light, and they had succeeded beyond their most sanguine expectations. Seventeen Allied ships were sunk and another eight were damaged, causing Bari to be dubbed the ’second Pearl Harbor.’ The Americans sustained the highest losses, losing the Liberty ships John Bascom, John L. Motley, Joseph Wheeler, Samuel J. Tilden and John Harvey. The British lost four ships, the Italians three, the Norwegians three and the Poles two.

2guerr3867The next morning survivors woke to a scene of utter devastation. Large parts of Bari had been reduced to rubble, particularly the medieval old town. Portions of the city and the harbor were still burning, and a thick pall of black smoke hung in the sky. There were more than 1,000 military and merchant marine casualties; about 800 were admitted to local hospitals. The full extent of civilian casualties may never be known. Conservative estimates hover around 1,000, though there were probably more.

bari-harbour-attackFortunately, Bari was the site of several Allied military hospitals and related support facilities. Some were housed at the Bari Polyclinic, built by Mussolini as a showcase of Fascist health care. The Polyclinic was home to the 98th British General Hospital and the 3rd New Zealand Hospital, among others. Those facilities received many of the mustard gas victims that began to appear.

Casualties from the raid began pouring in until the hospitals were filled to overflowing. Almost immediately some of the wounded began to complain of ‘gritty’ eyes, and their condition worsened in spite of conventional treatment. Their eyes were swollen, and skin lesions began to appear. Swamped with wounded of all descriptions and still not realizing they were dealing with poison gas, hospital staffers allowed victims to remain in their oil-and-gas-soaked clothes for long periods.

bari-casualtyNot only were the victims severely burned and blistered from prolonged exposure, but their respiratory systems were also badly irritated. The mustard gas casualties were wracked with coughs and had real difficulty breathing, but the hospital staff seemed helpless in the face of this unknown ailment. Men started to die, and even those who did recover faced a long and painful convalescence. Temporary blindness, the agony of burns and a terrible swelling of the genitals produced both physical and mental anguish.

As the victims began to die, the doctors started to suspect that some kind of chemical agent was involved. Some physicians pointed fingers at the Germans, speculating that they had resorted to chemical warfare after all. A message was sent to Allied headquarters in Algiers informing Deputy Surgeon General Fred Blesse that patients were dying of a ‘mysterious malady.’ To solve the mystery, Blesse dispatched Lt. Col. Stewart Francis Alexander, an expert on chemical warfare medicine, to Bari.

Alexander examined the patients and interviewed them when appropriate. It was beginning to look like mustard gas exposure, but the doctor was not sure. His suspicions were confirmed when a bomb-casing fragment was recovered from the bottom of the harbor. The fragment was identified as an American M47A1 bomb, which was designated for possible delivery of mustard gas. The Germans could be eliminated as suspects; in this case, the Allies were to blame.

Alexander still did not know where the mustard bombs had originated. The doctor tallied the number of mustard deaths in each ship, then plotted the position of the ships in the harbor. Most of the victims came from ships anchored near John Harvey. British port authorities finally admitted off the record that they knew John Harvey was carrying poison gas. Alexander drew up a report detailing his findings, which was approved by Allied Supreme Commander General Dwight D. Eisenhower. [7] This would be the only episode of exposure to a chemical warfare agent during WWII. By the end of the month, 83 of the 628 hospitalized military mustard gas victims had died.

gravesSecrecy still dogged the whole affair, however. Eventually, the British and American people were told of the devastating Bari raid, but the part played by mustard gas was kept from them. British Prime Minister Winston S. Churchill was particularly adamant that this aspect of the tragedy remain a secret. It was embarrassing enough that the raid occurred at a port under British jurisdiction. Churchill believed that publicizing the fiasco would hand the Germans a propaganda coup.

Although the gas was mentioned in official American records, Churchill insisted British medical records be purged and mustard gas deaths listed as the result of ‘burns due to enemy action.’ Churchill’s attempts at secrecy may have caused more deaths, because had the word gone out, more victims, especially Italian civilians, might have sought proper treatment. Axis Sally, the infamous propaganda broadcaster, learned the truth and taunted the Allies. ‘I see you boys are getting gassed by your own poison gas,’ she sneered.

There were 628 mustard gas casualties among Allied military and merchant marine personnel. Of these, 69 died within two weeks. Most victims, however, like Captain Heitmann of John Bascom, fully recovered. But the figures do not include the uncounted Italian civilians who must have been exposed to the deadly chemical. There was a mass exodus of civilians out of the city after the raid. Some were probably gas victims who died for want of proper treatment.

[1]. Encyclopedia of the First World War: Deaths from gas attacks, http://www.spartacus.schoolnet.co.uk/FWWgasdeaths.htm
[2]. Kumbhaar EB, Kumbhaar HD. The blood and bone marrow in Yellow Cross Gas (Mustard Gas) poisoning: Changes produced in the bone marrow of fatal cases. J Med Res 40:497-507,1919.
[3]. Pappenheimer AM, Vance M. The effects of intravenous injections of Di-Chloroethylsulfide in rabbits, with special reference to its leukotoxic action. J Exp Med 31:71-95,1920.
[4]. Berenblum I. Experimental inhibition of tumor induction by mustard gas and other compounds. J Path Bact 40:549-558,1935.
[5]. Einhorn J. Nitrogen mustard: The origin oc chemotherapy for cancer. Int J Radiation Oncologt Biol Phys 11:1375-1378,1985.
[6]. Goodman LS, Wintrobe MM, Dameshek W, et al. Use of methyl-bis- (β-chloroethyl) amine hydrochloride and tris-(β-chloroethyl) amine hydrochloride for Hodgkin’s disease, lymphosarcoma, leukemia, and certain allied and miscellaneous disorders. JAMA 132:126-132,1946.
[7]. Alexander SF. Medical report of the Bari Harbor Mustard casualties. The Military Surgeon 10:2-17,1947.

chemo-originsChemo origins

how-do-oncologists-sleep-at-nightHow do oncologists sleep at night?

is-chemotherapy-harmful-to-the-immune-systemIs chemotherapy harmful to the immune system?

dr-gonzalez-explains-why-chemo-is-so-ineffectiveDr Gonzalez Explains why chemo is so ineffective

high-priced-chemo-limited-benefit-youre-deadHigh priced chemo limited benefit…..you die

dr-jimenez-chemo-3-percentDr Jimenez chemo 3 percent effective

all-chemotherapy-agents-are-carcinogenicsAll chemotherapy agents are carcinogenics

chemotherapy-is-not-effective-for-90-percent-of-cancersChemotherapy is Not Effective for 90 Percent of Cancers

the-failure-of-chemotherapy-a-chemist-perspectiveThe failure of chemotherapy a chemist perspective

how-effective-is-chemotherapy-for-most-patientsHow effective is chemotherapy for most patients

audio-after-3-rounds-of-chemo-failure-a-4th-round-is-just-stupidAfter 3 rounds of chemo failure a 4th round is just stupid

chemo-side-effectsChemo Side Effects

the-shocking-cause-of-death-for-countless-cancer-patients-is-chemotherapyChemo as a cause of death

the-shocking-cause-of-death-for-countless-cancer-patients-is-chemotherapyChemo as a cause of death

patients-pressured-by-oncologistPatients pressured by oncologist

the-failure-of-high-dose-chemotherapyThe failure of high dose chemotherapy

the-main-reason-why-chemotherapy-failsThe Main Reason Why Chemotherapy Fails

how-successful-are-clinical-trialsHow successful are clinical trials?

excited-about-a-clinical-trial-not-so-fastExcited about a clinical trial? Not so fast

cbs-news-optimism-about-chemoCBS news optimism about chemo?

am-i-doing-what-is-best-for-the-patientAm I doing what is best for the patient?

does-chemo-cause-cancer-gonzalesDoes chemotherapy cause cancer?

is-stage-4-cancer-curable-using-chemotherapy-radiation-or-surgeryIs Stage 4 Cancer curable using Chemotherapy Radiation or Surgery

chemo-drugs-threats-to-health-care-workersChemo Drugs Threats to Health Care Workers

chemo-radiation-and-surgery-are-largely-ineffectiveChemo Radiation and Surgery are largely ineffective

how-hazardous-are-chemo-and-radiationHow hazardous are chemo and radiation

chemo-journeyChemo Journey

chemo-kills-just-as-many-people-as-cancerChemo Kills Just as Many People as Cancer

how-effective-is-typical-oncologyHow effective is typical oncology

chemo-and-radiation-are-killing-cancer-patientsChemo and radiation are killing cancer patients

chemo-and-radiation-are-non-specificChemo and radiation are non specific

chemotherapy-is-a-waste-of-moneyChemotherapy is a Waste of Money

dr-desaulniers-2-percent-chemo-effective-rateDr Desaulniers 2 percent chemo effective rate

is-chemo-really-97-percent-ineffectiveIs Chemo really 97 percent ineffective

chemo-is-carcinogenicChemo is carcinogenic

chemo-surgery-and-radiation-are-not-very-effectiveChemo surgery and radiation are not very effective

chemo-will-only-to-cure-2-percent-this-yearChemo will only to cure 2 percent this year

chemotherapy-chemist-secretsChemotherapy Chemist Secrets

chemotherapy-can-boost-cancer-growth-foxChemotherapy can boost cancer growth Fox

chris-wark-chemotherapy-causes-more-cancerChris Wark Chemotherapy Causes More Cancer

chemotherapy-really-is-poisonChemotherapy really is poison

does-it-make-sense-to-use-carcinogens-to-treat-cancerDoes it make sense to use carcinogens to treat cancer

dr-lodi-conventional-medicine-doesnt-workDr Lodi Conventional medicine doesnt work

chemo-scientific-american-john-cairnsChemo Scientific American John Cairns

fda-has-never-approved-chemo-or-radiation-for-childrenFDA has never approved chemo or radiation for children

oncology-mindsetOncology Mindset

half-of-all-drugs-are-recalledHalf of all drugs are recalled

audio-cancer-docs-talk-about-ineffective-chemoAudio Cancer docs talk about ineffective chemo

no-real-progress-against-cancerNo-real-progress-against-Cancer

criminal-doctor-farid-fata-confronted-by-misdiagnosed-patientsCriminal Doctor Farid Fata confronted by misdiagnosed patients

deception-at-dukeDeception at Duke

doctors-get-cancer-tooDoctors get cancer too

criminal-doctor-faces-prison-after-giving-unneeded-chemoCriminal Doctor faces prison after giving unneeded chemo

criminal-doctor-giveCriminal Doctor gives chemo to healthy patients

criminal-doctor-pleads-guilty-to-chemo-fraudCriminal Doctor pleads guilty to Chemo fraud

criminal-oncologist-prescribed-chemo-to-healthy-patients-for-moneyCriminal Oncologist prescribed chemo to healthy patients for money

fake-prescription-drugs-are-wide-spread-problemFake Prescription Drugs are wide spread problem

even-us-doctors-buy-unapproved-and-fake-cancer-drugsEven US doctors buy unapproved and fake cancer drugs

fake-avastin-cancer-drug-sold-by-doctorsFake Avastin cancer drug sold by doctors

abc-news-counterfeit-cancer-drugsABC news Counterfeit Cancer Drugs

fake-cancer-drugs-originate-in-chinaFake cancer drugs originate in China

60-minutes-the-fight-against-counterfeit-drugs60 Minutes the fight against counterfeit drugs

fake-drugs-confiscated-by-nbi-and-fdaFake drugs confiscated by NBI and FDA

inside-the-deadly-pakistan-counterfeit-drug-tradeInside the deadly Pakistan counterfeit drug trade

watered-down-chemo-drugs-in-canadaWatered down chemo drugs in Canada

watered-down-chemo-gets-pharmacist-30-years-in-prisonWatered down chemo gets Pharmacist 30 years in prison

watered-down-chemo-in-australiaWatered down chemo in Australia

watered-down-chemo-in-the-usWatered down chemo in the US

abc-news-the-prevalence-of-hospital-errorsABC news the prevalence of hospital errors

are-there-frauds-in-cancer-treatmentAre there frauds in Cancer treatment

99-percent-of-oncologists-still-dont-understand-nutrition99 Percent of Oncologists Still Dont Understand Nutrition

drugs-are-made-to-make-moneyDrugs are made to make money

fda-approval-doesnt-mean-its-safeFDA approval doesnt mean its safe

oncologist-bonus-structureOncologist Bonus structure

cancer-drugs-are-very-expensiveCancer drugs are very expensive

off-label-prescribingOff Label Prescribing

how-much-does-chemotherapy-costHow much does chemotherapy cost

big-pharma-financial-drivers-of-education-and-careBIG PHARMA Financial drivers of education and care

how-much-money-is-in-oncology-gonzalesHow much money is in oncology Gonzales

how-much-money-should-be-spent-for-minimal-chemo-benefitHow much money should be spent for minimal chemo benefit

big-pharma-big-money_documentary-on-the-money-and-corruption-of-big-pharmaceutical-companiesWhy chemo is so hard to recover from

chemotherapy-boosting-cancer-growthChemotherapy Boosting Cancer Growth

blind-faith-in-science-is-often-misplacedBlind faith in science is often misplaced

blind-obedience-can-kill-you-question-your-doctorBlind obedience can kill you question your doctor

chris-wark-medicine-is-not-science-basedChris Wark Medicine is NOT Science Based

be-confident-on-your-chosen-treatmentBe confident on your chosen treatment

Facebook
Google+
Twitter
YouTube
Instagram
 

To access the drfarrahcancercenter.com site, you must agree to the following;

Terms of Use

OVERVIEW

Please read these Terms of Use carefully before accessing or using our website. By accessing or using any part of the site, you agree to be bound by these Terms of Use. If you do not agree to all the terms and conditions of this agreement, then you may not access the website or use any services.

This website is operated by private parties in the Republic of Panama. Throughout the site, the terms “we”, “us” and “our” refer to drfarrahcancercenter.com, which offers this website, including all information, tools and services available from this site to you, the user, conditioned upon your acceptance of all terms, conditions, policies and notices stated here.

You understand and agree that you are accessing a website registered, owned, and hosted in the Republic of Panama. Therefore, all issues of a legal nature fall under the jurisdiction of the Republic of Panama legal system.

You understand and agree that as an authorized user you may only access information to which you have the legal authority to view and use. drfarrahcancercenter.com will monitor and record activity on this system to protect the system and its information and may use that monitoring information for official administrative or legal purposes. You understand and agree that you are not permitted to record, screenshot, or disseminate any information contained on the drfarrahcancercenter.com website to any party for any purpose whatsoever, and as such, you agree not to engage in such banned activities.

You understand and agree that unauthorized use of the system such as gaining unauthorized access to data, changing data, causing harm to the system or its data, or misuse of components is prohibited and may result in criminal, civil, or administrative penalties.

You also understand that drfarrahcancercenter.com can suspend or stop your use of this system if drfarrahcancercenter.com suspects any unauthorized use of the system attributable to you has occurred.

Your access to and use of the drfarrahcancercenter.com site is conditioned on your acceptance of and compliance with these Terms. These terms apply to all visitors, users and others who access or use the drfarrahcancercenter.com site. By accessing or using the drfarrahcancercenter.com site, you agree to be bound by these Terms. If you disagree with any part of the following Terms of Use, then you may not access the drfarrahcancercenter.com site.

By visiting our site and/ or purchasing anything from us, you engage in our “Service” and agree to be bound by the following terms and conditions (“Terms of Use”, “Terms”), including those additional terms and conditions and policies referenced herein and/or available by hyperlink. These Terms of Use apply to all users of the site, including without limitation users who are browsers, vendors, customers, merchants, and/ or contributors of content.

Any new features or tools which are added to the current website shall also be subject to the Terms of Use. You can review the most current version of the Terms of Use at any time on this page. We reserve the right to update, change or replace any part of these Terms of Use by posting updates and/or changes to our website. It is your responsibility to check this page periodically for changes. Your continued use of or access to the website following the posting of any changes constitutes acceptance of those changes.

 

SECTION 1 – ONLINE WEBSITE TERMS

By agreeing to these Terms of Use, you represent that you are at least the age of majority in your state, province, country or city of residence, or that you are the age of majority in your state, province, country or city of residence and you have given us your consent to allow any of your minor dependents to use this site.

You may not use any of our website for any illegal or unauthorized purpose nor may you, in the use of the Service, violate any laws in your jurisdiction (including but not limited to copyright laws).

You must not transmit any worms or viruses or any code of a destructive nature.

A breach or violation of any of the Terms will result in an immediate termination of your Services.

 

SECTION 2 – GENERAL CONDITIONS

We reserve the right to refuse service to anyone for any reason at any time.

You agree not to reproduce, duplicate, copy, sell, resell or exploit any portion of the Service, use of the Service, or access to the Service or any contact on the website through which the service is provided, without express written permission by us.

The headings used in this agreement are included for convenience only and will not limit or otherwise affect these Terms.

You understand and agree that this website is for information purposes only, and that by providing the information contained herein, we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. You understand and agree that before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

You understand and agree that the information on the site is presented for the sole purpose of disseminating health information for general educational purposes only. You understand and agree that if you think you may have a medical emergency, you should call your doctor or 911. You understand and agree that the information on this site is not intended or implied to be medical advice, and you understand and agree that the information does not constitute the provision or practice of medical, nursing, or professional health care advice or services. You understand and agree that you will not use the information on this site as a substitute for professional medical advice, diagnosis, or treatment. You understand and agree that you should always seek the advice of your physician or other qualified health care provider prior to starting any treatment or with any questions you may have regarding a medical condition.

You understand and agree that nothing contained on this site is intended to be or will be used by you for medical diagnosis or treatment. You understand and agree that you should never disregard professional medical advice or delay in seeking treatment based on the information contained on this site. You understand and agree that the service and any content or information contained on the site is provided on an ‘as is’ basis. You understand and agree that while efforts have been made to assure the accuracy of the information on this site, there is no guarantee that such information is accurate or up-to-date. You understand and agree that, except for information, products, or services clearly identified as being supplied by the site, the site does not operate, control, or endorse any information, products, or services on the internet, in any way.

In addition, access to this site constitutes acceptance and understanding of the following,

By accessing this system, you hereby acknowledge, consent, and agree to all listed provisions and consent to monitoring.

You understand and agree that any copyright laws pertaining to the ownership and reproduction of all data fall exclusively under Panamanian legal jurisdiction for drfarrahcancercenter.com

If you are a copyright holder, or a director, officer, owner, employee, agent, supplier, licensor, contributor, service provider, website hosting company, trade partner, heir or assign of a copyright holder and feel that you or anyone you are engaged in any form of relationship whatsoever may have rights to data as part of this site or related sites, your agreement with the terms of use constitutes the following agreement, which is mandatory in order to access the data contained on this site.

I do hereby declare, understand, agree and warrant that I am a copyright owner, or an authorized representative of a copyright owner of film, print, slide, movie, video, artwork, digital image, negatives or any other material in any format whatsoever (hereafter referred to as “COPYRIGHTED DATA”) which I believe to be, known to be, or suspect to be contained on the drfarrahcancercenter.com website.

I hereby freely grant a non-exclusive license to drfarrahcancercenter.com and its agents to reproduce these COPYRIGHT DATA in perpetuity, and I represent and warrant that I have the legal right and authority to grant such a license. I may at my discretion ask to be credited for my contribution or the contributor I represent to the drfarrahcancercenter.com site as a contributor whether this occurred with or without my knowledge, but even if I or the contributor I represent remains uncredited, this agreement shall survive since participation in the free flowing of information for the public at large is a paramount responsibility we all should share. Therefore, in the best interest of free-flowing information for the public at large, I am freely undertaking this agreement, and clearly warrant that I have the authority to do so. I agree to indemnify and hold harmless drfarrahcancercenter.com and any of its directors, officers, owners, employees, agents, suppliers, licensors, contributors, service providers, website hosting companies, trade partners, heirs and assigns from any and all liability, damages, and expenses (including reasonable actual attorney’s fees) that may incur as a result of use and publication of said material, including any claims brought by any person claiming an interest in the COPYRIGHTED DATA or their subject matter. I agree and warrant that anyone containing any format of data from drfarrahcancercenter.com contained in any medium outside of the drfarrahcancercenter.com website itself, is bound by this agreement, since acceptance of this agreement is the only way to legally access such data. In addition, I understand and agree that accessing or storing any format of data contained in any medium outside of the drfarrahcancercenter.com website where it is hosted, constitutes a violation of the copyright laws of Panama against the offending party. I understand and agree that if I copy, contain, possess, or transmit any such data from the drfarrahcancercenter.com site in any format outside of the website itself, that my possession of such materials is a violation of Panamanian laws, and I agree to destroy such data forthwith.

 

SECTION 3 – ACCURACY, COMPLETENESS AND TIMELINESS OF INFORMATION

We are not responsible if information made available on this site is not accurate, complete or current. The material on this site is provided for general information only and should not be relied upon or used as the sole basis for making decisions without consulting primary, more accurate, more complete or more timely sources of information. Any reliance on the material on this site is at your own risk.

This site may contain certain historical information. Historical information, necessarily, is not current and is provided for your reference only. We reserve the right to modify the contents of this site at any time, but we have no obligation to update any information on our site. You agree that it is your responsibility to monitor changes to our site.

 

SECTION 4 – MODIFICATIONS TO THE SERVICE

We reserve the right at any time to modify or discontinue the Service (or any part or content thereof) without notice at any time.

We shall not be liable to you or to any third-party for any modification, change, suspension or discontinuance of the Service.

 

SECTION 5 – OPTIONAL TOOLS

Any use by you of optional tools offered through the site is entirely at your own risk and discretion and you should ensure that you are familiar with and approve of the terms on which tools are provided by the relevant third-party provider(s).

We may also, in the future, offer new services and/or features through the website (including, the release of new tools and resources). Such new features and/or services shall also be subject to these Terms of Use.

 

SECTION 6 – THIRD-PARTY LINKS

Certain content, products and services available via our Service may include materials from third-parties.

Third-party links on this site may direct you to third-party websites that are not affiliated with us. We are not responsible for examining or evaluating the content or accuracy and we do not warrant and will not have any liability or responsibility for any third-party materials or websites, or for any other materials, products, or services of third-parties.

We are not liable for any harm or damages related to the purchase or use of goods, services, resources, content, or any other transactions made in connection with any third-party websites. Please review carefully the third-party’s policies and practices and make sure you understand them before you engage in any transaction. Complaints, claims, concerns, or questions regarding third-party products should be directed to the third-party.

 

SECTION 7 – USER COMMENTS, FEEDBACK AND OTHER SUBMISSIONS

If, at our request, you send certain specific submissions (for example contest entries) or without a request from us you send creative ideas, suggestions, proposals, plans, or other materials, whether online, by email, by postal mail, or otherwise (collectively, ‘comments’), you agree that we may, at any time, without restriction, edit, copy, publish, distribute, translate and otherwise use in any medium any comments that you forward to us. We are and shall be under no obligation (1) to maintain any comments in confidence; (2) to pay compensation for any comments; or (3) to respond to any comments.

We may, but have no obligation to, monitor, edit or remove content that we determine in our sole discretion are unlawful, offensive, threatening, libelous, defamatory, pornographic, obscene or otherwise objectionable or violates any party’s intellectual property or these Terms of Use.

You agree that your comments will not violate any right of any third-party, including copyright, trademark, privacy, personality or other personal or proprietary right. You further agree that your comments will not contain libelous or otherwise unlawful, abusive or obscene material, or contain any computer virus or other malware that could in any way affect the operation of the Service or any related website. You may not use a false e-mail address, pretend to be someone other than yourself, or otherwise mislead us or third-parties as to the origin of any comments. You are solely responsible for any comments you make and their accuracy. We take no responsibility and assume no liability for any comments posted by you or any third-party.

 

SECTION 8 – ERRORS, INACCURACIES AND OMISSIONS

Occasionally there may be information on our site or in the Service that contains typographical errors, inaccuracies or omissions that may relate to product descriptions, pricing, promotions, offers, product shipping charges, transit times and availability. We reserve the right to correct any errors, inaccuracies or omissions, and to change or update information or cancel orders if any information in the Service or on any related website is inaccurate at any time without prior notice (including after you have submitted your order).

We undertake no obligation to update, amend or clarify information in the Service or on any related website, including without limitation, pricing information, except as required by law. No specified update or refresh date applied in the Service or on any related website, should be taken to indicate that all information in the Service or on any related website has been modified or updated.

 

SECTION 9 – PROHIBITED USES

In addition to other prohibitions as set forth in the Terms of Use, you are prohibited from using the site or its content: (a) for any unlawful purpose; (b) to solicit others to perform or participate in any unlawful acts; (c) to violate any international, federal, provincial or state regulations, rules, laws, or local ordinances; (d) to infringe upon or violate our intellectual property rights or the intellectual property rights of others; (e) to harass, abuse, insult, harm, defame, slander, disparage, intimidate, or discriminate based on gender, sexual orientation, religion, ethnicity, race, age, national origin, or disability; (f) to submit false or misleading information; (g) to upload or transmit viruses or any other type of malicious code that will or may be used in any way that will affect the functionality or operation of the Service or of any related website, other websites, or the Internet; (h) to collect or track the personal information of others; (i) to spam, phish, pharm, pretext, spider, crawl, or scrape; (j) for any obscene or immoral purpose; or (k) to interfere with or circumvent the security features of the Service or any related website, other websites, or the Internet. We reserve the right to terminate your use of the Service or any related website for violating any of the prohibited uses.

 

SECTION 10 – DISCLAIMER OF WARRANTIES; LIMITATION OF LIABILITY

We do not guarantee, represent or warrant that your use of our service will be uninterrupted, timely, secure or error-free.

We do not warrant that the results that may be obtained from the use of the service will be accurate or reliable.

You agree that from time to time we may remove the service for indefinite periods of time or cancel the service at any time, without notice to you.

You expressly agree that your use of, or inability to use, the service is at your sole risk. The service and all products and services delivered to you through the service are (except as expressly stated by us) provided ‘as is’ and ‘as available’ for your use, without any representation, warranties or conditions of any kind, either express or implied, including all implied warranties or conditions of merchantability, merchantable quality, fitness for a particular purpose, durability, title, and non-infringement.

In no case shall anyone affiliated with drfarrahcancercenter.com including our directors, officers, employees, affiliates, agents, contractors, interns, suppliers, service providers or licensors be liable for any injury, loss, claim, or any direct, indirect, incidental, punitive, special, or consequential damages of any kind, including, without limitation lost profits, lost revenue, lost savings, loss of data, replacement costs, or any similar damages, whether based in contract, tort (including negligence), strict liability or otherwise, arising from your use of any of the service or any products procured using the service, or for any other claim related in any way to your use of the service or any product, including, but not limited to, any errors or omissions in any content, or any loss or damage of any kind incurred as a result of the use of the service or any content (or product) posted, transmitted, or otherwise made available via the service, even if advised of their possibility. Because some states or jurisdictions do not allow the exclusion or the limitation of liability for consequential or incidental damages, in such states or jurisdictions, our liability shall be limited to the maximum extent permitted by law.

You understand and agree that no singular individual, group of individuals or entity in any form whatsoever is responsible or liable in any manner for any content generated on, for, or as a result of the existence of this site, since this is a community generated site. You understand and agree that as this is a community generated site, and as a result of this, there is no good way to control what users and contributors post on or through the sites and drfarrahcancercenter.com cannot be responsible for any offensive, inappropriate, obscene, unlawful, infringing or otherwise objectionable or even illegal user generated content you may encounter on the sites or, in connection with your use of the sites.

You understand and agree with the following statement made on behalf of drfarrahcancercenter.com, “We, on behalf of our directors, officers, employees, agents, suppliers, licensors, contributors and service providers, exclude and disclaim liability for any losses and expenses of whatever nature and howsoever arising including, without limitation, any direct, indirect, general, special, punitive, incidental or consequential damages; loss of use: loss of data; loss caused by a virus: loss of income or profit: loss of or damage to property: loss of life: claims of third parties: or other losses of any kind or character, or the inability to use, the site or the content even if we have been advised of the possibility of such damages or losses, arising out of or in connection with the use of this site or any web site with which it is linked.”

 

SECTION 11 – INDEMNIFICATION

You agree to indemnify, defend and hold harmless drfarrahcancercenter.com and our parent, subsidiaries, affiliates, partners, officers, directors, agents, contractors, licensors, service providers, subcontractors, suppliers, interns and employees, harmless from any claim or demand, including reasonable attorneys’ fees, made by any third-party due to or arising out of your breach of these Terms of Use or the documents they incorporate by reference, or your violation of any law or the rights of a third-party.

 

SECTION 12 – SEVERABILITY

In the event that any provision of these Terms of Use is determined to be unlawful, void or unenforceable, such provision shall nonetheless be enforceable to the fullest extent permitted by applicable law, and the unenforceable portion shall be deemed to be severed from these Terms of Use, such determination shall not affect the validity and enforceability of any other remaining provisions.

 

SECTION 13 – TERMINATION

The obligations and liabilities of the parties incurred prior to the termination date shall survive the termination of this agreement for all purposes.

These Terms of Use are effective unless and until terminated by us. You may terminate use of the drfarrahcancercenter.com site, but this Terms of Use shall survive in perpetuity.

If in our sole judgment you fail, or we suspect that you have failed, to comply with any term or provision of these Terms of Use, we also may terminate this agreement at any time without notice and you will remain liable for all amounts due up to and including the date of termination; and/or accordingly may deny you access to our Services (or any part thereof).

 

SECTION 14 – ENTIRE AGREEMENT

The failure of us to exercise or enforce any right or provision of these Terms of Use shall not constitute a waiver of such right or provision.

These Terms of Use and any policies or operating rules posted by us on this site or in respect to The Service constitutes the entire agreement and understanding between you and us and govern your use of the Service, superseding any prior or contemporaneous agreements, communications and proposals, whether oral or written, between you and us (including, but not limited to, any prior versions of the Terms of Use).

Any ambiguities in the interpretation of these Terms of Use shall not be construed against the drafting party.

 

SECTION 15 – GOVERNING LAW

These Terms of Use and any separate agreements whereby we provide you Services shall be governed by and construed in accordance with the laws of the Republic of Panama.

 

SECTION 16 – CHANGES TO TERMS OF USE

You can review the most current version of the Terms of Use at any time at this page.

We reserve the right, at our sole discretion, to update, change or replace any part of these Terms of Use by posting updates and changes to our website. It is your responsibility to check our website periodically for changes. Your continued use of or access to our website or the Service following the posting of any changes to these Terms of Use constitutes acceptance of those changes.

 

SECTION 17 – CONTACT INFORMATION

Questions about the Terms of Use should be sent to us at staff@drfarrahcancercenter.com

Upon agreeing to these terms and conditions, you gain access to the drfarrahcancercenter.com website and assume total responsibility for any and all actions undertaken by you as a result of your access to the drfarrahcancercenter.com website. You agree and understand that the terms of this agreement shall be binding upon you, your respective heirs, successors, assigns and legal representatives. You understand and agree that all provisions of this Terms of Use agreement that by their nature should survive termination shall survive termination, including, without limitation, ownership provisions, warranty disclaimers, indemnity, licensing in perpetuity and limitations of liability.