IMMUNOTHERAPY AND CANCER
According to the National Cancer Institute, immunotherapy is defined as a treatment to boost or restore the ability of the immune system to fight cancer, infections, and other diseases.
There Are 2 Types of Immunotherapy for Cancer
ACTIVE IMMUNOTHERAPY
Active immunotherapy engages the immune system and is typically very durable. An excellent example is the protocol we developed known as Multiphasic Intravenous Antigen Presentation Immunomodulation.
PASSIVE IMMUNOTHERAPY
Passive immunotherapy enhances pre-existing immune response and has a short life. Examples include monoclonal antibodies and cytokines.
Immunotherapy is Proven Effective in Cancer
Immunotherapies, such as monoclonal antibodies, checkpoint inhibitors, cytokines, and therapeutic vaccines, have been approved by the FDA to treat certain cancers.2
FDA-APPROVED IMMUNOTHERAPIES*,2-6
Class | Approvals |
---|---|
Monoclonal antibodies | 1997, 1998, 2000, 2001, 2002, 2003, 2004, 2006, 2009 |
Checkpoint inhibitor | 2011 |
Cytokines | 1986, 1992, 1995, 1998 |
Therapeutic vaccine | 2010 |
*Not inclusive of all immunotherapy classes.
REFERENCES
- Rescigno M, Curigliano G, et al. Biochim Biophys Acta. 2007;1776(1):108-123.
- Mellman I, Dranoff G, et al. Nature. 2011;480(7378):480-489.
- Kirkwood JM, Ferrone S, et al. CA Cancer J Clin. 2012;62(5):309-335.
- Lotze M. In: Cancer: Principles & Practice of Oncology. 9th ed. 2011.
- Sondak VK, Hauschild A, et al. In: Cancer: Principles & Practice of Oncology. 9th ed. 2011.
- Robinson MK, Weiner LM, et al. In: Cancer: Principles & Practice of Oncology. 9th ed. 2011.